Study finds common, targetable mechanism which tumors use to suppress immune responses — ScienceDaily

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer…

T cells that ‘nibble’ tumors unwittingly help cancer evade the immune response — ScienceDaily

The immune system is equipped to respond not just to external invaders — think viruses, bacteria, and parasites — but also to internal threats, namely, cancer. Yet, frequently, malignancies overcome…

‘Drug factory’ implants eliminate mesothelioma tumors in mice — ScienceDaily

Rice University and Baylor College of Medicine researchers have shown they can eradicate advanced-stage mesothelioma tumors in mice in just a few days with a treatment combining Rice’s cytokine “drug…

A ‘weak spot’ discovered that potentially makes multi-drug resistant tumors vulnerable — ScienceDaily

One of the greatest challenges facing cancer researchers is to understand why some patients don’t respond to treatments. In some cases, tumors exhibit what is known as multidrug resistance (MDR),…

Colorectal cancer tumors both helped and hindered by T cells — ScienceDaily

Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated. While some studies have shown that white blood cells heroically…

Proteomic study of 2,002 tumors identifies 11 pan-cancer molecular subtypes across 14 types of cancer — ScienceDaily

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online…

ATF4 protein works in tumors and tumor-supporting fibroblasts to promote tumor survival — ScienceDaily

A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future…

Solid tumors use a type of T cell as a shield against immune attack — ScienceDaily

An unexpected trick in cancer’s playbook may fool an important component of our immune systems into knocking down our natural defenses against solid tumors. Scientists at Fred Hutchinson Cancer Center…

T cell behavior determines which tumors respond to treatment — ScienceDaily

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn’t work, and new research may help explain why. When immune cells called T…

The strategy may make tumors more vulnerable to anti-cancer therapies — ScienceDaily

Tiny structures called nanoparticles can be used to carry substances to certain parts of the body — for example, to deliver a chemotherapy drug to a tumor. Although such “nanomedicine”…