Targeting T cells and myeloid cells together improved anti-tumor response and survival in preclinical models — ScienceDaily

Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel immunotherapy combination, targeting checkpoints in both T cells and myeloid suppressor cells, that successfully reprogrammed the…

A common dietary fiber promotes allergy-like immune responses in preclinical studies — ScienceDaily

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung…

Anthelmintic inhibits exacerbated inflammatory response related to COVID-19 in preclinical research

Experiments involving animals and human cells conducted at the University of São Paulo (USP) in Brazil suggest that niclosamide, an anthelmintic widely used against tapeworms, effectively inhibits SARS-CoV-2 replication as…

Preclinical study reveals that immune cells in the brain could be possible new drug targets for ASD and intellectual disability — ScienceDaily

University at Buffalo scientists have discovered a convergent mechanism that may be responsible for how two top-ranked genetic risk factors for autism spectrum disorder/intellectual disability (ASD/ID) lead to these neurodevelopmental…

Clinical trial is planned based on results from preclinical study. — ScienceDaily

In type 1 diabetes, an autoimmune response attacks the pancreas’s insulin-producing beta cells, leading to marked fluctuations in blood sugar levels. Lifelong daily insulin treatments are standard for patients, but…